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  Thyroid Science 5(4):CLS1-4, 2010


FDG-PET/CT Visualizes a
Case of Primary Hyperparathyroidism in a
Patient with Gastrointestinal Stromal Tumor


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Laura Evangelista,1,2 Anna Rita Cervino,1
Michele Gregianin,1 Giorgio Saladini1


1Department of Radiotherapy and Nuclear Medicine Service,
Istituto Oncologico Veneto, Padova, Italy.
2Department of Biomorphological and Functional Sciences,
University Federico II, Napoli, Italy


*Correspondence author: Laura Evangelista
Istituto Oncologico Veneto, IOV, I.R.C.C.S., Via Gattamelata, 64, 35128 Padova, Italy
Tel: +39 3396687579; Fax: +39 049 821 2205
laura.evangelista@tin.it

Abstract. Background. Positron emission tomography/computed tomography (PET/CT) is used in clinical practice above all other tests to define the status of oncological disease. The predominant use of PET/CT is due to its use of 18F- fluorodeoxyglucose (FDG) to map cellular glucose metabolism. Some benign clinical conditions are also detected with FDG-PET/CT. These include inflammatory or hypermetabolic processes. Parathyroid adenoma is the most common cause of primary hyperparathyroidism, and nuclear medicine is already used to locate adenomas and to guide surgery for their removal. The utility of PET/CT with 11C-methionine for parathyroid disorders is well-documented in the research literature, while the usefulness of PET/CT with 18F-FDG is not clear. Case Presentation. We reported a case of a patient without specific symptoms for primary hyperparathyroidism, with a borderline high value of parathyroid hormone and a positive finding of parathyroid disease with PET/CT using 18F-FDG. Conclusion. PET/CT with 18F-FDG is useful in identifying parathyroid adenomas, and the techniques can be used to precisely clarify the nature of suspected nodules close to thyroid gland.

Keywords Adenoma Computerized tomography 18F-Fluorodeoxyglucose 11C-Methionine Oncological disease Parathyroid hormone Parathyroidism Positron emission tomography

 

Evangelista, L., Cervino, A.R., Gregianin,M., and Saladini, G.: FDG-PET/CT Visualizes a case of primary hyperparathyroidism in a patient with gastrointestinal stromal tumor. Thyroid Science, 5(4):1-4, 2010.

Full Text Free in pdf format

2010 Thyroid Science