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The Metabolic Treatment
of Fibromyalgia
by Dr. John C. Lowe
Readers' Comments
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He and his research team
determined that the two main underlying causes of the documented
symptoms and objective features of fibromyalgia are hypothyroidism
and/or peripheral thyroid hormone resistance.
Dr. Lowe is author of the internationally acclaimed book
The Metabolic Treatment of Fibromyalgia. The book is
considered by many to be the most important document every published on
fibromyalgia. At the same time, the book comprehensively covers basic
and clinical thyroidology.
In addition to conducting studies, Dr. Lowe also provides
long-distance educational consulting for clinicians, fibromyalgia
patients, and other patients with hypothyroidism or thyroid hormone
resistance.
Biography
Dr. Lowe holds B.A. and M.A. degrees in
research-oriented general psychology from the University of West
Florida. He also holds a B.S. degree in human biology and a doctorate in
chiropractic from the Los Angeles College of Chiropractic, now the
Southern California University of Health Sciences. He formerly taught
psychology at the Miami Dade Community College and was a faculty member
in the Clinical Sciences Division of the Texas Chiropractic College.
Clinical Licenses. Dr.
Lowe has been a chiropractic physician since 1977. At different times in
his clinical career, he was licensed to practice in Florida, Texas, and
Colorado. He was originally licensed to practice in 1978; he voluntarily
gave up his final clinical license on January 1, 2010.
Dr. Lowe had long decided (some ten years before) to strategically give up his licenses
at a certain point in his career. He was well prepared for that point,
having been advised and tutored about it by many of his medical colleagues
who had been defrocked by their regulatory boards and courts for resisting the use of T4 replacement therapy
and actually helping thyroid patients recover their health.
The predetermined point to forfeit his licenses was clearly defined: it
was when it became his evidence-based opinion that
a corrupt chiropractic board and/or corrupt judicial officials
were arranging to try to silence him from his constant reports of the
corruption and incompetence of the endocrinology specialty in dealing
with hypothyroidism and thyroid hormone resistance.
Dr. Lowe used a calculated judo approach to what he believes was finally an unscrupulous attempt to silence him.
By using this long planned approach, he avoided much of the
apparently work-distracting and resource-draining intentions of his opponents.
At that point, he gave up his clinical licenses, thereby
removing from his forehead the license-based target for the snipers of
corruption. Giving up the licenses caused
him and his family no hardship and little distraction, as he had
long prepared for this eventuality. As he had often warned, the attempt to silence him merely freed
him to speak
more often and more vociferously about the horrors imposed on humanity
by the endocrinology specialty and its Big Pharma
sponsors.
Rather than direct clinical care, Dr. Lowe now continues his many-years practice of informational/educational consulting with clinicians and patients.
He provides them with information the patients need to achieve optimal health. His main focus in informational consulting is the safe and effective use of thyroid hormone,
but he also provides consultations on health in general.
Publications. Dr. Lowe has authored more than 160 articles, scientific papers, and book chapters. His writings have appeared many journals, including
Psychological Reports; Medical Science Monitor; the
Journal of Behavior Therapy and Experimental Psychiatry; the
American Journal of Pain Management;
Anabolism—A Journal of Preventive Medicine; Medical Hypotheses;
Lyon Méditerranée Médical: Médecine du Sud-Est; the British Medical
Journal; the Journal of Myofascial Therapy; the
Clinical Bulletin of Myofascial Therapy; the Massage
Therapy Journal; the Journal of the American Chiropractic
Association; and Thyroid Science. Trade papers such
as Dynamic Chiropractic, the Chiropractic Journal, and others
have published articles and monthly columns by Dr. Lowe.
The authors of at least
twenty-three books
have cited or described Dr. Lowe's work. Among his own published books
are
Spasm,
Your Guide to Metabolic Health, and
The Metabolic Treatment of Fibromyalgia. Study Sphere gave Dr.
Lowe its
Excellence Award
for his chapter in
The Metabolic Treatment of
Fibromyalgia
in which he shows that fibromyalgia is not a psychiatric
disorder. In the chapter, he refutes the notion that fibromyalgia is a
mental or emotional disorder. He also argues that the misdiagnosis is
usually a product of the psychological disturbance of physicians who
make the misdiagnosis.
Awards and Memberships.
In 1977, the American Chiropractic Association awarded Dr. Lowe its
Annual Scientific Paper Award. In 1992, for his contributions to the
field of myofascial therapy, the National Association of Myofascial
Trigger Point Therapists appointed him an honorary lifetime member. He
has served as an official scientific reviewer on the International
Reviewers' Panel of
Medical Science Monitor, an international journal for
experimental and clinical research. As a reviewer, he did critical
reviews of submitted research papers in the fields of hypothyroidism and
thyroid hormone resistance.
Dr. Lowe is a member of the Board of Medical Advisors of Thyroid UK, and
is a member of
Index Copernicus Scientists, a
global information networking system for scientists. He is
Editor-in-Chief of the open-access journal
Thyroid Science (www.ThyroidScience.com),
which publishes papers on the full range of topics in thyroidology. He
formerly served on the Advisory Board of Inside Texas Running
Magazine and the Editorial Review Board of the Journal of
Bodywork and Movement Therapies. He is a former editor of the
Journal of Myofascial Therapy and the Clinical Bulletin of
Myofascial Therapy.
In December 2005, Dr. Lowe became a member of
Index Copernicus Scientists upon invitation from its CEO Mark R.
Graczynski, MD, PhD. Index Copernicus Scientists is a global information
networking system for scientists, designed by and for scientists.
According to Dr. Graczynski, “The aim of this web-based communication
platform is to offer a set of essential tools to encourage the effective
exchange of information between scientists worldwide as well as to promote
and initiate international research collaboration.” He also notes, “The
system encourages the effective exchange of information between scientists
worldwide as well as to promote and initiate international research
collaboration.”
Dr. Lowe's line of metabolism research over the last twenty years led to two
significant outcomes: First was
the solution to the problem of fibromyalgia, showing that its main
underlying mechanism is too little thyroid hormone regulation, often
complicated by nutritional deficiencies, low physical fitness, an
unwholesome diet, blood sugar dysregulation, and the use of
metabolism-impeding drugs; second was his creation and coining of “metabolic
rehabilitation,” a high-precision, data-driven clinical approach for helping
patients to improve or recover. His hope is that his interaction within the
community of international scientists through Index Copernicus Scientists
will lead to researchers in other countries becoming involved in the line of
metabolic research he began and continues.
The 62nd edition of the premier biographical source
Marquis Who's Who in American was published in 2008. (For a
history and description and Marquis, and its committee's process
of selecting individuals to include, see
Wikipedia's
article on Marquis.) Dr. Lowe was selected by the Marquis
committee to be included.
Marquis, which began publication in 1899, chronicles the lives and
careers of men and women their committee considers noteworthy Americans.
(Dr.
Lowe's comments on his inclusion in Marquis.)
Marriages. Before he married Tammy Lewis, Dr. Lowe had said
on this webpage that his marriages had been best exemplified by a song
of the
Allman Brothers' Band. However, on June 8th, 2009, he said:
"Today, Tammy and I received another email from someone courteously
asking whether that song refers to our marriage. The answer is a
resounding no! I should have clarified that on the webpage long
ago."
Tammy's and my relationship," he said, "was so good before we married that I was afraid
to do it; I didn't want to risk the pressures of life together within
marriage spoiling what we had. That misgiving was entirely wrong. What
seemed the best of all possible relationships for me has, since we
married, steadily grown into even more. She slipped through my fingers
more than twenty years ago, but after she and I reunited again after
some 18 years, I wasn't about to make that mistake again. Marriage to
Tammy has made my life better than I ever imagined it could be. I
cherish her and our marriage more than I can find words to express, and
it's all the better because of our beautiful daughter, Michele, whom we
had in 1984. This assessment of our marriage is especially noteworthy in
that we've long passed the time that the newness typically wears off."
I know that as human beings, we're all fallible," Dr. Lowe said. "Because we are, I accept in
stride the mistakes I've made in life and their punitive
consequences—that is, all but one mistake: not having talked Tammy into
marrying me all those years ago. But it's a mistake now joyfully
rectified."
Underpinnings of Dr. Lowe's Work. Underpinning Dr. Lowe's work are his two main intellectual interests: (1)
theoretical-deductive science, which enables one to make the best possible
sense of study findings in a research field; and (2) symbolic (mathematical)
logic, the discipline one uses to determine the validity or invalidity of
his own and others' conclusions and arguments.
Dr. Lowe is a devout critical
rationalist. This means that he subscribes to the hypothesis (proposed by
Sir Karl Popper and articulated by David Miller and others) that the
ultimate job of logical, scientific thinkers is to formulate bold
hypotheses, and rigorously try to falsify them. The reason for falsifying
the hypotheses is to eliminate errors in them and perhaps the entire
hypotheses. Free of at least some of their errors, ideas, beliefs,
hypotheses, and theories may become more accurate representations of truth,
which is correspondence with truth. If eliminating errors makes it obvious
that an idea, belief, hypothesis, or theory is entirely false, then we can—having
learned from the falsification—replace it with one that is hopefully
more accurate.
He is also an active critical
analyst. This means that he logically analyzes his own thinking and beliefs
and those of others to learn whether or not these are accurate and rational.
In recent years, drug and medical device corporations have largely co-opted
medical research, the medical profession and its institutions, medical
practice guidelines committees, and the US Congress. These corporations have
essentially turned all of these groups, to varying degrees, into marketing
tools for the products of the corporations. This phenomenon is the basis of
the statement that the major motive behind science today is economics rather
than curiosity and problem solving. This corruption of science has brought
about a necessity for patients and clinicians to protect themselves from
marketing disguised as scientific findings. Through critical analyses, Dr.
Lowe is exposing such marketing disguised as science in the fields of
fibromyalgia and thyroidology.
Examples of Dr. Lowe's critical analyses are his critiques of
the T4 vs T4/T3 studies;
the false and potentially harmful beliefs
of the self-proclaimed "real
thyroid expert," Dr. Richard Guttler
the
British Thyroid Associations presentation of selective and false
evidence in advocating T4 replacement over treatment with desiccated
thyroid; and
Dr. Guttler's false claims about natural desiccated thyroid.
History.
Dr. Lowe began using
myofascial therapy in 1980 under the tutelage of the late chiropractic
radiologist and clinician David Ramby, D.C. For years, Dr. Lowe's main
clinical focus was patients' chronically tense muscles, fascial adhesions,
and myofascial trigger points. To help these patients, he used a
broad-spectrum therapeutic approach. It included soft tissue manipulative
techniques, Travell and Simons's stretch and spray, clinical nutrition, and
various physical therapy modalities, especially ultrasound. After studying
"perpetuating factors" (factors that make myofascial patients treatment
resistant) as described by Drs. Janet Travell and David Simons (especially
in the 1st edition of their famous Trigger Point Manual published in
1983), he began tenaciously studying biochemical abnormalities that render
some patients resistant to otherwise effective myofascial therapy.
While studying the role of thyroid hormone deficiency in treatment
resistance of myofascial pain syndromes, Dr. Lowe found that hypothyroid
fibromyalgia patients usually recover from their fibromyalgia symptoms when
treated in one or both of two ways: (1) a thyroid hormone dosage greater
than a replacement dose (the amount needed to keep the TSH level within the
dubious "normal" range), and (2) with desiccated thyroid or T3 rather than
the customarily prescribed T4 (thyroxin). He also found that most
fibromyalgia patients who aren't hypothyroid also improve or recover without
overstimulation when treated with fairly high dosages of plain as opposed to
sustain-release T3. These patients can be said to be partially resistant to
thyroid hormone.
In 1995, one of Dr. Lowe's patients who had recovered from her fibromyalgia
symptoms through his metabolic approach convinced him to established the
Fibromyalgia Research Foundation
(FRF). The three purposes of this 501(c)(3) nonprofit organization are to:
(1) support scientific studies of the metabolic treatment of fibromyalgia
patients; (2) determine the underlying molecular mechanisms of fibromyalgia;
and (3) educate fibromyalgia patients, clinicians, researchers, and
the general public about the findings of FRF-sponsored research.
FRF's charter requires the
organization both conduct and publish research and educate patients,
clinicians, other researchers, and the general public about fibromyalgia.
Complying with this requirement, Dr. Lowe has remained vocal about what his
research group determined to the ultimate creator of what we call
fibromyalgia. That ultimate creator is T4 replacement therapy. The therapy
is so mistakenly conceived and clinically ineffective that since the early
1970s, when it first imposed on thyroid patients, a range of mysterious new
diseases have been reported. Published research shows that the plausible
mechanism most of these conditions is too little thyroid hormone regulation.
In 2006, Dr. Lowe published
the first two studies that showed that on average, female fibromyalgia
patients had resting metabolic rates about 30% below normal.
fibromyalgia patients. In two studies published in 2006 (for the publishes
study report, see
Medical Science Monitor [scroll down to "Clinical Research"]
and
Thyroid Science). The studies also showed that fibromyalgia
patients had significantly lower basal body temperatures than those of
healthy controls. In two ways, results of these studies vindicate Dr. Lowe's
hypothesis of fibromyalgia in two ways: (1) the studied found that
fibromyalgia patients are hypometabolic, and (2) that the most likely
mechanism of the patients' symptoms is too little thyroid hormone
regulation.
Dr. Lowe has also determined
that some
90% of fibromyalgia patients have thyroid disease. The thyroid diseases
include primary hypothyroidism, central hypothyroidism, and partial
peripheral cellular resistance to thyroid hormone. Most hypothyroid patients
fully recover when they undergo the metabolic rehabilitation using natural
desiccated thyroid or T3 alone. And most fibromyalgia patients with thyroid
hormone resistance markedly improve or fully recover when they go through
metabolic rehab and use T3.
Dr. Lowe is firm that he has
determined the underlying mechanisms of most patients' fibromyalgia. Peter
Warmingham of Thyroid UK pointed this out in 2002 in his article titled
"Fibromyalgia has been solved" (Fibro Focus Supporter, 3:1-3, 2002).
Dr. Lowe repeated Mr. Warmingham's announcement on August 19, 2005 in
Sugarland, Texas at the
Functional Endocrinology Symposium (sponsored by the Professional
Compounding Companies of America), and he reiterated it on May 25, 2007 at
the endocrinology symposium of the Institute for Functional Medicine in
Tucson, Arizona. Overwhelming scientific evidence supports Mr. Warmingham's
and Dr. Lowe's announcements.
Dr. Lowe's Curriculum Vitae |